Simultaneous multi-nuclide imaging via double-photon coincidence method with parallel hole collimators

Abstract Multi-tracer imaging can provide useful information in the definitive diagnosis and research of medical, biological, pharmaceutical sciences. Single-photon emission computed tomography (SPECT) is one nuclear medicine modalities widely used for or medical has a multi-tracer capability. One drawbacks crosstalk from other gamma rays, which affects reconstructed image. Scattering correction methods, such as dual- triple-energy window are conventional SPECT to reduce background caused by crosstalk. This study proposes another reduction method. Some nuclides emit two more rays through intermediate levels. Thus, detecting these with coincidence method allows us distinguish true ray signal signal. The nuclide position be estimated at intersection using collimators. We demonstrate herein simultaneous 111 In 177 Lu via double-photon GAGG detectors parallel hole greatly reduces offers higher-quality images than does imaging.